Personalized Medicine’s 20th Anniversary: From Promise to Practice

November 30 – December 1, 2023 • Ritz-Carlton Laguna Niguel, Dana Point, CA



Reflections and Visions

7:30 a.m.
Registration and Breakfast
8:30 a.m.
Opening Remarks

SPEAKER | Edward Abrahams, Ph.D., President, Personalized Medicine Coalition

8:35 a.m.
The Past, Present, and Future of Personalized Medicine: Keynote Reflections from Scott Gottlieb, Senior Fellow at the American Enterprise Institute

For many Americans, Scott Gottlieb has become a household name in health care. He is a former commissioner of the Food and Drug Administration. He made frequent media appearances during the Covid-19 pandemic. And in 2019, he oversaw a record number of new personalized medicine approvals. During this opening keynote address, Gottlieb will reveal his latest thinking about the future of personalized medicine and discuss what it needs to advance.

INTRODUCTION | Lauren Silvis, J.D., Senior Vice President, External Affairs, Tempus

KEYNOTE SPEAKER | Scott Gottlieb, M.D., Senior Fellow, American Enterprise Institute; New York Times best-selling author, Uncontrolled Spread: Why COVID-19 Crushed Us and How We Can Defeat the Next Pandemic

9:15 a.m.
Investing in Personalized Medicine

Game-changing early detection technologies. Wearable health monitoring devices. Gene editing. Investors see tantalizing possibilities in personalized medicine. But the path to profitability is fraught with challenges. During this session, a panel of investors will consider the future of investment in personalized medicine.


Vineeta Agarwala, M.D., Ph.D., General Partner, Andreessen Horowitz

Tom Miller, Managing Partner, GreyBird Ventures

Michael J. Pellini, M.D., Managing Partner, Section 32

10:00 a.m.
Networking Break
10:30 a.m.
The Broad Horizons of Personalized Medicine: A Range of Approaches Influencing the State of Play

Many companies are widening the frontiers of personalized medicine. Ultima Genomics wants to make sequencing cheaper and more broadly accessible. Siemens executives see an expanded role for imaging biomarkers to target therapies to those who will benefit. And at Kyverna Therapeutics, scientists are exploring how to extend the benefits of cell-based immunotherapies to patients with autoimmune diseases. During this session, executives from each of these companies will explain how their work may expand the boundaries of personalized medicine.


Christian Eusemann, Vice President, Research and Innovation, North America, Siemens Healthineers

Josh Lauer, Chief Commercial Officer, Ultima Genomics

Peter Maag, Ph.D., CEO, Kyverna Therapeutics

11:15 a.m.
Presentation of the 18th Annual Award for Leadership in Personalized Medicine

The Annual Award for Leadership in Personalized Medicine recognizes an individual whose contributions in science, business, and policy have helped advance the frontiers of the field.



12:00 p.m.
Lunch Buffet in the Monarch Courtyard and Pool
1:00 p.m.
Paying for Personalized Medicine

Innovators in personalized medicine are struggling to convince health insurance executives that paying more for tests and treatments today will decrease health spending in the future by keeping patients healthier, longer. While serving as Chief Medical Officer for regional health insurer Point32Health from 2011 to March of 2023, Michael Sherman repeatedly broke this bottleneck by signing innovative reimbursement agreements with diagnostics and therapeutics developers who are willing to share in the financial risks of piloting coverage for new medical products. During this session, Sherman will reflect on what it takes to move the reimbursement needle in ways that benefit both patients and health systems.

INTRODUCTION | Cynthia A. Bens, Senior Vice President, Public Policy, Personalized Medicine Coalition

SPEAKER | Michael Sherman, M.D., Venture Partner, RA Capital Management

1:45 p.m.
Developing Diagnostics for Personalized Medicine

Diagnostics companies provide a backbone for personalized medicine by developing the tests necessary to target the right preventive and treatment interventions to the right patients at the right times. Testing innovators today face daunting challenges along with promising new opportunities to impact health care. During this panel discussion, industry executives will consider the future of diagnostic test development.

MODERATOR | Kimberly Popovits, Board Member, 10x Genomics

Helmy Eltoukhy, Ph.D., Chairman, co-CEO, Guardant Health

Phil Febbo, M.D., Chief Medical Officer, Illumina

Chad Robins, Chairman, CEO, Adaptive Biotechnologies

Jay G. Wohlgemuth, M.D., Chief Medical Officer Emeritus, Senior Medical Advisor, Quest Diagnostics

2:30 p.m.
Creating Personalized Medicines

The pharmaceutical industry stands four-square behind personalized medicine. PMC’s latest research shows that personalized medicines accounted for at least 25 percent of new U.S. Food and Drug Administration-approved drugs for each of the last eight years. But economic and political landscapes are shifting. During this panel discussion, industry executives will discuss how they are continuing to cultivate their pipelines while adapting to dynamic circumstances across the globe.

MODERATOR | Randy Burkholder, Vice President, Policy and Research, PhRMA

Gabriele Allegri, Global Commercial Head, Precision Medicine, The Janssen Pharmaceutical Companies of Johnson & Johnson

Steffan Ho, M.D., Ph.D., Vice President, Head of Translational Oncology, Pfizer

Tamar Thompson, Vice President, Head of Corporate Affairs, Alexion/AstraZeneca Rare Disease

3:15 p.m.
Networking Break
3:45 p.m.
Improvements in Clinical Care Associated With Personalized Medicine: PMC Releases New Research Results

Leaders in clinical care are eager to understand whether clinical integration programs in personalized medicine will improve the lives of their patients. During this presentation, the Personalized Medicine Coalition will unveil the preliminary results of a study designed to evaluate whether the clinical integration efforts of United States health systems that score higher on a peer-reviewed survey measuring multi-factorial clinical adoption of personalized medicine are driving superior clinical outcomes for their patients.

MODERATOR | Daryl Pritchard, Ph.D., Senior Vice President, Science Policy, Personalized Medicine Coalition

Gary Gustavsen, Partner, Health Advances

4:00 p.m.
Clinical Adoption of Personalized Medicine: Progress and Lessons Learned in the United States and Europe

For clinical care providers, personalized medicine may present opportunities to improve care for their patients and make better use of scare resources by targeting treatments to those who will benefit. But spearheading the clinical adoption of personalized medicine is anything but easy. During this panel discussion, researchers, business leaders, and clinicians who are intimately involved in the clinical integration of personalized medicine will reflect on the pace of progress in the United States and Europe.

MODERATOR | Lincoln Nadauld, M.D., Ph.D., President, CEO, Culmination Bio

Antonio L. Andreu, M.D., Ph.D., Scientific Director, European Infrastructure for Translational Medicine (EATRIS)

Thomas Brown, M.D., Chief Medical Officer, Syapse

Catherine Hajek, M.D., Internal Medicine Physician, Sanford Health; Medical Director, Helix

Howard McLeod, Pharm.D., Managing Director, Clarified Precision Medicine

4:45 p.m.
The Past, Present, and Future of Personalized Medicine: Keynote Reflections From Amy Abernethy, Chief Medical Officer and President of Product Development at Verily

As a Chief Medical Officer responsible for the health care business of one of the world’s largest technology companies, Amy Abernethy, formerly Principal Deputy Commissioner at the U.S. Food and Drug Administration, sits at the intersection of the rapidly converging industries of medicine, technology, and digital health. During this closing keynote address, Abernethy will explain her vision of a future in which collaborative leaders deploy advanced computational tools, artificial intelligence, and remote data collection technologies to unleash the full potential of personalized medicine for every patient.


KEYNOTE SPEAKER | Amy Abernethy, M.D., Ph.D., Chief Medical Officer, President, Product Development, Verily, an Alphabet company

5:30 p.m.
Welcome Reception on the Dana Point Lawn

Sponsored by


Executing in a New Era

7:30 a.m.
Registration and Breakfast
8:30 a.m.
Opening Remarks

SPEAKER | Lincoln Nadauld, M.D., Ph.D., President, CEO, Culmination Bio

8:35 a.m.
The Future of Personalized Medicine and the Pharmaceutical Industry: A Keynote Interview With Gilead Sciences CEO Daniel O’Day

With the development of paradigm-shifting targeted medicines and cell-based immunotherapies, Gilead Sciences is helping to blaze a trail for personalized medicine. During this keynote interview, Daniel O’Day, who serves as the CEO of the $27 billion company, will share his thoughts about the future of personalized medicine and the pharmaceutical industry.


KEYNOTE SPEAKER | Daniel O’Day, Chairman, CEO, Gilead Sciences (invited)

9:15 a.m.
The Future of Personalized Medicine and the Diagnostics Industry: A Keynote Interview With Labcorp CEO Adam Schechter

As a company whose diagnostic tests, drug development services, and technological solutions touch the care trajectories of more than 120 million patients across more than 100 countries each year, Labcorp’s thinking about the future of health and medicine will have a profound impact on the contours of patient care for years to come. During this keynote interview, CEO Adam Schechter will discuss his perspectives on the future of personalized medicine and the diagnostics industry.


KEYNOTE SPEAKER | Adam Schechter, Chairman, President, CEO, Labcorp

10:00 a.m.
Networking Break
10:30 a.m.
Patients’ Perspectives on Personalized Medicine

When it comes to medicine, no one knows better than patients that one size does not fit all. During this wide-ranging fireside chat, two cancer survivors — one, a journalist, and the other, a patient advocate — will reflect on the status of health care in America.


Kathy Giusti, Founder, Multiple Myeloma Research Foundation

Karen Tumulty, Deputy Editorial Page Editor, The Washington Post

11:15 a.m.
Multi-Cancer Early Detection Technologies: When and How Should They Be Integrated into Health Care?

By giving physicians an easy way to detect early-stage cancers anywhere in the body, blood-based multi-cancer early detection (MCED) tests might help physicians and patients get ahead of a disease that is the second-leading cause of death in the United States today. But it could take years of research to confirm their clinical and economic benefits. In this context, researchers and industry executives will close the conference with a discussion about when and how one of the most promising tools shaping thinking about the future of personalized medicine should be integrated into health care to benefit patients with little time to waste.


Tomasz Beer, M.D., Vice President, Chief Medical Officer, Multi-Cancer Early Detection, Exact Sciences

Josh Ofman, M.D., President, Grail

Kathryn Phillips, Ph.D., Professor, Founding Director of the Center for Translational and Policy Research on Precision Medicine, University of California, San Francisco

Wendy Rubinstein, M.D., Ph.D., Senior Scientist, Division of Cancer Prevention, National Cancer Institute

12:00 p.m.
Closing Remarks

SPEAKER | Edward Abrahams, Ph.D., President, Personalized Medicine Coalition

12:05 p.m.
Lunch Buffet in the Monarch Courtyard and Pool